Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338379 | 0.89 | NPSR1 (0.35) | MAPTATMSMN1; SMN2LMNAUSP2 | |
| SCHEMBL9337948 | 0.85 | HSD17B10 (0.42) | MAPTATMSMN1; SMN2LMNAUSP2 | |
| SCHEMBL9338473 | 0.84 | CYP1A1 (0.37) | MAPTATMSMN1; SMN2LMNAUSP2 | |
| SCHEMBL9342353 | 0.81 | AR (0.44) | MAPTATMSMN1; SMN2LMNAUSP2 | |
| SCHEMBL9337865 | 0.81 | POLB (0.37) | MAPTATMSMN1; SMN2LMNAUSP2 | |
| SCHEMBL9338126 | 0.81 | SMN1; SMN2 (0.43) | MAPTATMSMN1; SMN2LMNAUSP2 | |
| SCHEMBL9339766 | 0.80 | LMNA (0.42) | MAPTATMSMN1; SMN2LMNANPC1 | |
| SCHEMBL9342213 | 0.79 | SMN1; SMN2 (0.54) | MAPTATMSMN1; SMN2LMNANPSR1 | |
| SCHEMBL9337765 | 0.79 | LMNA (0.41) | MAPTATMSMN1; SMN2LMNAKMT2A | |
| SCHEMBL9338690 | 0.79 | LMNA (0.41) | MAPTATMSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |