Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338523 | 0.89 | MAPT (0.41) | NPSR1USP2HSD17B10PLK1MAPT | |
| SCHEMBL9337865 | 0.82 | POLB (0.37) | NPSR1USP2HSD17B10PLK1MAPT | |
| SCHEMBL9338473 | 0.82 | CYP1A1 (0.37) | NPSR1USP2HSD17B10PLK1MAPT | |
| SCHEMBL9341646 | 0.82 | CYP1A1 (0.45) | NPSR1MAPTSMN1; SMN2LMNAATM | |
| SCHEMBL9338349 | 0.82 | DPP4 (0.39) | MAPTSMN1; SMN2LMNAATMALDH1A1 | |
| SCHEMBL9337948 | 0.79 | HSD17B10 (0.42) | NPSR1USP2HSD17B10PLK1MAPT | |
| SCHEMBL9342353 | 0.75 | AR (0.44) | NPSR1USP2HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL9338572 | 0.74 | MAOB (0.56) | NPSR1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10497499 | 0.74 | THRA (0.39) | KMT2ATHRBMEN1CYP1A2 | |
| SCHEMBL9338126 | 0.74 | SMN1; SMN2 (0.43) | NPSR1USP2HSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |