Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960871 | 0.91 | CA12 (0.62) | CA12CA1CA2CA9GAA | |
| SCHEMBL9334531 | 0.84 | CA12 (0.50) | CA12CA1CA2CA9GAA | |
| SCHEMBL9338670 | 0.84 | ALDH1A1 (0.54) | GAANPC1KMT2AMAPTLMNA | |
| SCHEMBL13381398 | 0.84 | CA12 (0.52) | CA12CA1CA2CA9GAA | |
| SCHEMBL5671993 | 0.83 | CA12 (0.60) | CA12CA1CA2CA9GAA | |
| SCHEMBL27631537 | 0.81 | GAA (0.54) | CA12CA1CA2CA9GAA | |
| SCHEMBL12724543 | 0.80 | CA12 (0.46) | CA12CA1CA2CA9GAA | |
| SCHEMBL14040323 | 0.80 | GAA (0.46) | CA12CA1CA2CA9GAA | |
| SCHEMBL30450762 | 0.80 | HPGD (0.64) | CA12CA1CA2CA9MMP8 | |
| SCHEMBL8031605 | 0.79 | ELANE (0.53) | CA12CA1CA2CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322236-B1 | Catalytic process for preparing optically active threonine | TAKASAGO PERFUMERY CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-4906773-A | Process for preparing optically active threonine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0322236-A2 | Catalytic process for preparing optically active threonine | Takasago International Corporation (JP) | 1989-06-28 | — | — | EP | disclosed |