Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10415112 | 1.00 | MAPT (0.57) | MAPTKMT2AELANEMAPK1HSD17B10 | |
| SCHEMBL17848853 | 0.87 | MAPT (0.54) | MAPTKMT2AELANEMAPK1HSD17B10 | |
| SCHEMBL17853801 | 0.86 | KDM4E (0.55) | MAPTKMT2AELANEMAPK1HSD17B10 | |
| SCHEMBL825544 | 0.85 | ELANE (0.71) | MAPTKMT2AELANEMAPK1HTT | |
| SCHEMBL10423088 | 0.85 | ELANE (0.50) | MAPTKMT2AELANEMAPK1ALDH1A1 | |
| SCHEMBL10423087 | 0.85 | ELANE (0.50) | MAPTKMT2AELANEMAPK1ALDH1A1 | |
| SCHEMBL825605 | 0.84 | ELANE (0.53) | MAPTKMT2AELANEALDH1A1 | |
| SCHEMBL14996055 | 0.84 | ELANE (0.50) | MAPTKMT2AELANEMAPK1TP53 | |
| SCHEMBL10000787 | 0.84 | ELANE (0.47) | MAPTKMT2AELANEHSD17B10TSHR | |
| SCHEMBL650639 | 0.84 | ELANE (0.50) | MAPTKMT2AELANEMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262809-B1 | Pyrimidinylphenyl ester compound | TEIKOKU CHEM IND CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4980082-A | DISPLAY ELEMENTS; HIGH SPEED RESPONSE TO ELECTRICAL FIELDS | SEIKO INSTRUMENTS INC. (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0262809-A1 | Pyrimidinylphenyl ester compound | TEIKOKU CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |