SCHEMBL10000787

SCHEMBL10000787

CCC(C)C(=O)Oc1ccc(-c2ccc(OC(=O)C(C)CC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.47
MAPT P10636 2/20 0.46
ESR1 P03372 2/20 0.43
HIF1A Q16665 2/20 0.43
HSD17B10 Q99714 1/20 0.42
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422503 0.93 HSD17B10 (0.53) ELANEMAPTHSD17B10KMT2AMEN1
SCHEMBL825538 0.93 MAPT (0.56) ELANEMAPTKMT2AMEN1CYP1A2
SCHEMBL15965768 0.93 LMNA (0.47) ELANEMAPTESR1HIF1AHDAC3
SCHEMBL9488299 0.93 ESR2 (0.44) ELANEMAPTESR1HIF1AHDAC3
SCHEMBL14781032 0.92 MAPT (0.48) ELANEMAPTHDAC3HDAC4HDAC1
SCHEMBL10422526 0.92 ESR1 (0.57) ELANEMAPTESR1HIF1AHSD17B10
SCHEMBL20614960 0.90 MAPT (0.54) ELANEMAPTESR1HIF1AHSD17B10
SCHEMBL14627817 0.89 MAPT (0.40) ELANEMAPTESR1HIF1AHSD17B10
SCHEMBL10423310 0.89 BCL9 (0.50) ELANEMAPTESR1HIF1AHSD17B10
SCHEMBL25968326 0.89 ELANE (0.61) ELANEESR1HIF1AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8455062-B2 Liquid crystal display panel and process for production thereof SHARP KABUSHIKI KAISHA (JP) 2013-06-04 US disclosed
US-20120113370-A1 Liquid Crystal Display Panel and Process for Production Thereof MERCK PATENT GMBH (DE) 2012-05-10 US disclosed