Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334783 | 0.91 | — | — | |
| SCHEMBL9335032 | 0.75 | — | — | |
| SCHEMBL9334886 | 0.73 | S1PR4 (0.30) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL9336494 | 0.72 | BACE1 (0.33) | — | |
| SCHEMBL9334918 | 0.70 | — | — | |
| SCHEMBL9516530 | 0.66 | — | — | |
| SCHEMBL9338567 | 0.65 | KDM4E (0.30) | — | |
| SCHEMBL9512139 | 0.61 | — | — | |
| SCHEMBL9336556 | 0.58 | ADRA2A (0.34) | — | |
| SCHEMBL9334851 | 0.58 | INMT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366969-A | Amidine group containing monocycloheteracyclic or bicycloheterocyclic diphosphonic acid derivatives and medicaments containing these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-11-22 | — | — | US | disclosed |
| EP-0491001-B1 | NEW DIPHOSPHONIC ACID DERIVATIVES CONTAINING AMIDINE GROUPS, PROCESS FOR PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1993-12-01 | — | — | EP | disclosed |
| WO-1991003481-A1 | NEW DIPHOSPHONIC ACID DERIVATIVES CONTAINING AMIDINE GROUPS, PROCESS FOR PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-03-21 | — | — | WO | disclosed |