SCHEMBL93388

SCHEMBL93388

COc1ccc(C(=O)c2ccc(O)cc2O)c(O)c1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.59
MAPT P10636 3/20 0.59
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
HPGD P15428 4/20 0.51
CYP3A4 P08684 3/20 0.51
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MAPK1 P28482 2/20 0.51
LMNA P02545 2/20 0.51
RECQL P46063 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
PDK2 Q15119 1/20 0.50
PDK4 Q16654 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5709936 0.89 NPC1 (0.56) TDP1MAPTNPC1RAB9AHPGD
SCHEMBL30374830 0.89 NPC1 (0.56) TDP1MAPTNPC1RAB9AHPGD
SCHEMBL27713896 0.87 MAPT (0.76) TDP1MAPTNPC1RAB9AHPGD
SCHEMBL5709924 0.85 NPC1 (0.50) TDP1MAPTNPC1RAB9AHPGD
SCHEMBL30375044 0.85 NPC1 (0.50) TDP1MAPTNPC1RAB9AHPGD
SCHEMBL5710222 0.84 HPGD (0.54) TDP1MAPTNPC1RAB9AHPGD
SCHEMBL30375533 0.84 HPGD (0.54) TDP1MAPTNPC1RAB9AHPGD
SCHEMBL93336 0.83 MAPT (0.61) TDP1MAPTNPC1RAB9AHPGD
SCHEMBL8484707 0.81 MAPT (0.63) TDP1MAPTHPGDCYP3A4KDM4E
SCHEMBL5710003 0.80 TUBB4A (0.59) MAPTNPC1RAB9AHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2428540-B1 Coating composition SHINETSU CHEMICAL CO (JP) 2018-02-21 EP disclosed
US-9862806-B2 Plastic article for automotive glazing SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2607413-B1 Plastic Substrate for Automotive Glazing and Its Repairing Method SHINETSU CHEMICAL CO (JP) 2017-06-21 EP disclosed
EP-2426175-B1 Plastic article for automotive glazing SHINETSU CHEMICAL CO (JP) 2014-07-23 EP disclosed
US-8642672-B2 Coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-02-04 US disclosed
US-20130164539-A1 PLASTIC SUBSTRATE FOR AUTOMOTIVE GLAZING AND ITS REPAIRING METHOD KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-06-27 US disclosed
EP-2607413-A1 Plastic Substrate for Automotive Glazing and Its Repairing Method Shin-Etsu Chemical Co., Ltd. (JP) 2013-06-26 EP disclosed
EP-2428540-A1 Coating composition Shin-Etsu Chemical Co., Ltd. (JP) 2012-03-14 EP disclosed
US-20120059080-A1 COATING COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
US-20120058347-A1 PLASTIC ARTICLE FOR AUTOMOTIVE GLAZING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
EP-2426175-A1 Plastic article for automotive glazing Shin-Etsu Chemical Co., Ltd. (JP) 2012-03-07 EP disclosed
EP-2300599-A4 AUGMENTATION OF CELL THERAPY EFFICACY INCLUDING TREATMENT WITH ALPHA 1-3 FUCOSLYTRANSFERASE AMERICAN STEM CELL INC (US) 2011-11-23 EP disclosed
US-8052900-B2 Reactive UV absorber, UV-screen film-forming curable coating solution, UV-screen film, and substrate having UV-screening function SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-11-08 US disclosed
EP-2182032-B1 Reactive UV absorber, UV-screen film-forming curable coating solution, UV-screen film, and substrate having UV-screening function SHINETSU CHEMICAL CO (JP) 2011-10-05 EP disclosed
US-20100108960-A1 REACTIVE UV ABSORBER, UV-SCREEN FILM-FORMING CURABLE COATING SOLUTION, UV-SCREEN FILM, AND SUBSTRATE HAVING UV-SCREENING FUNCTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-05-06 US disclosed
EP-2182032-A1 Reactive UV absorber, UV-screen film-forming curable coating solution, UV-screen film, and substrate having UV-screening function SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-05-05 EP disclosed