SCHEMBL30375533

SCHEMBL30375533

COc1cccc(C(=O)c2ccc(O)cc2O)c1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.54
LMNA P02545 2/20 0.54
CYP1A2 P05177 2/20 0.54
PGR P06401 2/20 0.54
SLC6A2 P23975 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP3A4 P08684 2/20 0.54
ALOX15 P16050 2/20 0.54
ADORA3 P0DMS8 1/20 0.54
AR P10275 1/20 0.54
CHRM1 P11229 1/20 0.54
TBXA2R P21731 1/20 0.54
ADRA1A P35348 1/20 0.54
HIF1A Q16665 1/20 0.54
TTR P02766 1/20 0.53
NR1H4 Q96RI1 3/20 0.53
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5710222 1.00 HPGD (0.54) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL7338664 0.90 NPC1 (0.69) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL5709936 0.88 NPC1 (0.56) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL30374830 0.88 NPC1 (0.56) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL5709859 0.86 LMNA (0.62) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL30320256 0.86 LMNA (0.62) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL29120698 0.84 LMNA (0.55) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL3762150 0.84 RAB9A (0.55) HPGDLMNANPC1RAB9ACA12
SCHEMBL93388 0.84 TDP1 (0.59) HPGDLMNACYP1A2PGRSLC6A2
SCHEMBL29393311 0.83 TTR (0.57) HPGDLMNACYP1A2PGRSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed