Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445493 | 0.91 | DGAT1 (0.34) | DGAT1ACACBHDAC4 | |
| SCHEMBL9343500 | 0.91 | DGAT1 (0.34) | DGAT1ACACBHDAC4 | |
| SCHEMBL9338880 | 0.91 | GRIN2B (0.35) | DGAT1ACACBDHODHHDAC4 | |
| SCHEMBL9338972 | 0.88 | FASN (0.33) | DGAT1 | |
| SCHEMBL9445500 | 0.88 | EP300 (0.36) | DGAT1KDM1AHDAC4 | |
| SCHEMBL9338924 | 0.88 | EP300 (0.36) | DGAT1KDM1AHDAC4 | |
| SCHEMBL9339576 | 0.87 | DGAT1 (0.34) | DGAT1DHODHHDAC4 | |
| SCHEMBL9338974 | 0.87 | DGAT1 (0.34) | DGAT1DHODHHDAC4 | |
| SCHEMBL9342749 | 0.85 | EGLN2 (0.39) | KDM1A | |
| SCHEMBL9338850 | 0.84 | DGAT1 (0.37) | DGAT1ACACBDHODHHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391591-B1 | Pyrimidine derivative and liquid crystal composition incorporating the same | SEIKO EPSON CORP (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0391591-A2 | Pyrimidine derivative and liquid crystal composition incorporating the same | SEIKO EPSON CORPORATION (JP) | 1990-10-10 | — | — | EP | disclosed |