Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7736550 | 0.89 | FASN (0.35) | FASNDGAT1ADORA2AADORA1GRM2 | |
| SCHEMBL7736554 | 0.89 | FASN (0.35) | FASNDGAT1ADORA2AADORA1GRM2 | |
| SCHEMBL9342749 | 0.89 | EGLN2 (0.39) | EGLN2 | |
| SCHEMBL9338964 | 0.88 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL9339413 | 0.86 | FASN (0.39) | FASNDGAT1ADORA2AADORA1GRM2 | |
| SCHEMBL9445493 | 0.86 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL9343500 | 0.86 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL9445468 | 0.86 | FASN (0.39) | FASNDGAT1ADORA2AADORA1GRM2 | |
| SCHEMBL9338880 | 0.86 | GRIN2B (0.35) | DGAT1 | |
| SCHEMBL9445492 | 0.84 | CYP2C9 (0.41) | FASNDGAT1ADORA2AADORA1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391591-B1 | Pyrimidine derivative and liquid crystal composition incorporating the same | SEIKO EPSON CORP (JP) | 1994-06-15 | — | — | EP | disclosed |