Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339227 | 0.85 | PTGER4 (0.58) | NPC1RAB9ASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL8139922 | 0.82 | NPC1 (0.68) | PKMHSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5580509 | 0.82 | LIPG (0.49) | PTGER4ALOX5APAKR1B1AKR1A1 | |
| SCHEMBL9335349 | 0.81 | CYSLTR1 (0.48) | NPC1RAB9ASMN1; SMN2MAPK1L3MBTL1 | |
| SCHEMBL9335068 | 0.78 | SMN1; SMN2 (0.53) | HSD17B10NPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL5512060 | 0.75 | MAOB (0.63) | SMN1; SMN2MRGPRX4NR4A2MAOB | |
| SCHEMBL12470685 | 0.75 | FFAR1 (0.52) | LMNAPKMHSD17B10NPC1RAB9A | |
| SCHEMBL8666834 | 0.74 | CSNK1D (0.48) | TRPV1NPC1RAB9ASMN1; SMN2ALOX5AP | |
| SCHEMBL5580777 | 0.74 | CSNK1D (0.51) | MRGPRX4CSNK1DAKR1B1 | |
| SCHEMBL9339010 | 0.74 | PTGER4 (0.56) | NPC1RAB9ASMN1; SMN2MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |