Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 3/20 | 0.59 |
| ▸ | ALB | P02768 | 3/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339206 | 0.98 | ICMT (0.57) | ICMTALBEPHX1ALDH1A1HTT | |
| SCHEMBL9337294 | 0.94 | HDAC6 (0.52) | ICMTALBEPHX1ALDH1A1HTT | |
| SCHEMBL9340742 | 0.87 | MEN1 (0.54) | ICMTALBALDH1A1NPSR1MEN1 | |
| SCHEMBL9435656 | 0.84 | CA12 (0.64) | ICMTALBEPHX1ALDH1A1HTT | |
| SCHEMBL25276969 | 0.84 | CA12 (0.64) | ICMTALBEPHX1ALDH1A1HTT | |
| SCHEMBL7611007 | 0.83 | ICMT (0.61) | ICMTALBEPHX1ALDH1A1HTT | |
| SCHEMBL7621060 | 0.83 | ICMT (0.61) | ICMTALBEPHX1ALDH1A1HTT | |
| SCHEMBL25226015 | 0.83 | ICMT (0.61) | ICMTALBEPHX1ALDH1A1HTT | |
| SCHEMBL10596306 | 0.83 | CA12 (0.61) | ICMTALBEPHX1ALDH1A1HTT | |
| SCHEMBL25272478 | 0.82 | ICMT (0.59) | ICMTALBEPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332750-A | Treatment of hypertension, aldosteronism, cardiac insufficienc y | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-07-26 | — | — | US | disclosed |
| EP-0530702-A1 | 1,2-dihydro-2-oxopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-03-10 | — | — | EP | disclosed |