Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | ICMT | O60725 | 2/20 | 0.62 |
| ▸ | ALB | P02768 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25276969 | 1.00 | CA12 (0.64) | CA12CA1CA2CA9ICMT | |
| SCHEMBL10596306 | 0.98 | CA12 (0.61) | CA12CA1CA2CA9ICMT | |
| SCHEMBL25272478 | 0.94 | ICMT (0.59) | CA12CA1CA2CA9ICMT | |
| SCHEMBL2448810 | 0.93 | HDAC6 (0.65) | CA12CA1CA2CA9ICMT | |
| SCHEMBL25277617 | 0.92 | HDAC6 (0.57) | CA12CA1CA2CA9ICMT | |
| SCHEMBL14228915 | 0.90 | HDAC6 (0.62) | CA12CA1CA2CA9ICMT | |
| SCHEMBL27745844 | 0.89 | CA12 (0.54) | CA12CA1CA2CA9ICMT | |
| SCHEMBL25272620 | 0.87 | HDAC6 (0.62) | CA12CA1CA2CA9ICMT | |
| SCHEMBL10596118 | 0.86 | ALDH1A1 (0.61) | CA12CA1CA2CA9ICMT | |
| SCHEMBL7621060 | 0.86 | ICMT (0.61) | CA12CA1CA2CA9ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283362-A | Reacting with an amine, terminating the reaction before the formation of by-product | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1994-02-01 | — | — | US | disclosed |