Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.57 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522667 | 1.00 | ALOX5 (0.59) | ALOX5F2RL1CALM1LTB4RIGF1R | |
| SCHEMBL20019549 | 0.98 | ALOX5 (0.61) | ALOX5F2RL1CALM1IGF1RALOX15 | |
| SCHEMBL659052 | 0.93 | ALOX5 (0.68) | ALOX5F2RL1CALM1POLBTAAR1 | |
| SCHEMBL8843136 | 0.88 | CNR1 (0.60) | ALOX5F2RL1CALM1 | |
| SCHEMBL1413843 | 0.87 | F2RL1 (0.68) | ALOX5F2RL1POLBTAAR1 | |
| SCHEMBL9235000 | 0.86 | ALOX5 (0.59) | ALOX5F2RL1CALM1LTB4RIGF1R | |
| SCHEMBL9484086 | 0.86 | LTB4R (0.69) | ALOX5F2RL1CALM1LTB4R | |
| SCHEMBL9663959 | 0.86 | LTB4R (0.69) | ALOX5F2RL1CALM1LTB4R | |
| SCHEMBL8003026 | 0.86 | ALOX5 (0.59) | ALOX5F2RL1CALM1LTB4RIGF1R | |
| SCHEMBL11637942 | 0.86 | ALOX5 (0.59) | ALOX5F2RL1CALM1LTB4RIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |