Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337608 | 0.97 | TERT (0.48) | TERTEPHX2LMNALTA4HPAX8 | |
| SCHEMBL9337581 | 0.97 | TERT (0.48) | TERTEPHX2LMNALTA4HPAX8 | |
| Formic Acid SCHEMBL9335926 | 0.96 | TERT (0.49) | TERTEPHX2LMNALTA4HPAX8 | |
| Formic Acid SCHEMBL9337592 | 0.93 | TERT (0.45) | TERTEPHX2LMNALTA4HPAX8 | |
| SCHEMBL9335651 | 0.86 | EPHX2 (0.47) | EPHX2LMNAPAX8GAAITGB3 | |
| SCHEMBL9335956 | 0.86 | TERT (0.48) | TERTEPHX2LMNALTA4HPAX8 | |
| Formic Acid SCHEMBL9339344 | 0.83 | EPHX2 (0.44) | EPHX2LMNAPAX8GAAITGB3 | |
| SCHEMBL9335980 | 0.83 | KMT2A (0.58) | EPHX2LMNAGAA | |
| SCHEMBL9337613 | 0.83 | TERT (0.44) | TERTEPHX2LMNALTA4HPAX8 | |
| SCHEMBL9335865 | 0.82 | MEN1 (0.56) | EPHX2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372486-B1 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | HOFFMANN LA ROCHE (CH) | 1994-06-01 | — | — | EP | claimed |