Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335651 | 0.96 | EPHX2 (0.47) | EPHX2PAX8LMNAITGB3ITGA2B | |
| Formic Acid SCHEMBL9337592 | 0.88 | TERT (0.45) | EPHX2PAX8LMNAITGB3ITGA2B | |
| Formic Acid SCHEMBL9335926 | 0.87 | TERT (0.49) | EPHX2PAX8LMNAITGB3GAA | |
| SCHEMBL9339361 | 0.87 | PAX8 (0.41) | EPHX2PAX8LMNAGAAF3 | |
| SCHEMBL9337608 | 0.84 | TERT (0.48) | EPHX2PAX8LMNAITGB3ITGA2B | |
| SCHEMBL9337581 | 0.84 | TERT (0.48) | EPHX2PAX8LMNAITGB3ITGA2B | |
| Formic Acid SCHEMBL9339307 | 0.83 | CASR (0.43) | ITGB3ITGA2BCASR | |
| SCHEMBL9339508 | 0.83 | TERT (0.53) | EPHX2PAX8LMNAITGB3GAA | |
| SCHEMBL19445842 | 0.82 | POLB (0.52) | LMNAGAAPARP1PARP10 | |
| Formic Acid SCHEMBL9335859 | 0.81 | POLB (0.48) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372486-B1 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | HOFFMANN LA ROCHE (CH) | 1994-06-01 | — | — | EP | claimed |
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |