Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 6/20 | 0.75 |
| ▸ | TYR | P14679 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339710 | 1.00 | CHRNA7 (0.75) | CHRNA7TYRMEN1ALDH1A1LMNA | |
| SCHEMBL9337637 | 0.89 | ALDH1A1 (0.65) | CHRNA7MEN1ALDH1A1LMNAGAA | |
| SCHEMBL9337650 | 0.89 | ALDH1A1 (0.65) | CHRNA7MEN1ALDH1A1LMNAGAA | |
| SCHEMBL1695380 | 0.86 | CHRNA7 (1.00) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL21446884 | 0.86 | CHRNA7 (1.00) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL1695381 | 0.86 | CHRNA7 (1.00) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL28606028 | 0.86 | MEN1 (0.62) | CHRNA7MEN1ALDH1A1LMNAGAA | |
| SCHEMBL9337678 | 0.85 | MAPT (0.60) | CHRNA7MEN1ALDH1A1LMNAGAA | |
| SCHEMBL9337658 | 0.85 | MAPT (0.60) | CHRNA7MEN1ALDH1A1LMNAGAA | |
| SCHEMBL9342731 | 0.84 | MAPT (0.59) | CHRNA7TYRMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |