Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 1.00 |
| ▸ | TYR | P14679 | 2/20 | 0.81 |
| ▸ | CTSL | P07711 | 2/20 | 0.65 |
| ▸ | CTSB | P07858 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.62 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | F3 | P13726 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21446884 | 1.00 | CHRNA7 (1.00) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL1695380 | 1.00 | CHRNA7 (1.00) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL21446825 | 0.90 | TYR (1.00) | CHRNA7TYRCTSLCTSBCAPN1 | |
| SCHEMBL3995353 | 0.90 | TYR (1.00) | CHRNA7TYRCTSLCTSBCAPN1 | |
| SCHEMBL7925073 | 0.90 | TYR (1.00) | CHRNA7TYRCTSLCTSBCAPN1 | |
| SCHEMBL28094310 | 0.86 | CHRNA7 (0.91) | CHRNA7TYRBACE1 | |
| SCHEMBL9339710 | 0.86 | CHRNA7 (0.75) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL1603828 | 0.86 | CHRNA7 (0.75) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL1603827 | 0.86 | CHRNA7 (0.75) | CHRNA7TYRCTSLCTSBTDP1 | |
| SCHEMBL9339702 | 0.86 | CHRNA7 (0.75) | CHRNA7TYRCTSLCTSBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9877946-B2 | Method for treating, managing, inhibiting, or preventing obesity | Research & Business Foundation Sungkyunkwan University (KR) | 2018-01-30 | — | — | US | claimed |
| US-20170087126-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVER SITY (KR) | 2017-03-30 | — | — | US | claimed |
| US-9549908-B2 | Composition for inducing differentiation into beige and brown adipocytes and method of inducing the same | Research & Business Foundation Sungkyunkwan University, Ltd. (KR) | 2017-01-24 | — | — | US | claimed |
| CN-104288133-B | 3,5-diisoamyl thiazolinyl, 2,4, the purposes of 4 '-trihydroxy chalcone and derivant thereof and preparation | TIANJIN UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2016-04-06 | — | — | CN | claimed |
| US-20150374643-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2015-12-31 | — | — | US | claimed |
| CN-104288133-A | 3,5-diisoamylene, 2,4,4'-trihydroxyl chalcone as well as use and preparation method of derivative of the 3,5-diisoamylene, 2,4,4'-trihydroxyl chalcone | UNIV TIANJIN SCIENCE & TECH | 2015-01-21 | — | — | CN | claimed |
| EP-1808172-A2 | Botanical extract compositions and methods of use | The Medical Research and Education Trust (US) | 2007-07-18 | — | — | EP | claimed |
| US-20050032882-A1 | Botanical extract compositions and methods of use | ACTIVEPHYTO TECHNOLOGIES LIMITED (GB) | 2005-02-10 | — | — | US | claimed |
| EP-1487434-A2 | BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER OR PHYTOESTROGENIC ACTIVITY COMPRISING WOGONIN, ISOLIQUIRITIGENIN AND/OR COUMESTROL | The Medical Research and Education Trust (US) | 2004-12-22 | — | — | EP | claimed |
| WO-2003075943-A2 | BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER OR PHYTOESTROGENIC ACTIVITY COMPRISING WOGONIN, ISOLIQUIRITIGENIN AND/OR COUMESTROL | THE MEDICAL RESEARCH AND EDUCATION TRUST (US) | 2003-09-18 | — | — | WO | claimed |
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | claimed |
| US-9877946-B2 | Method for treating, managing, inhibiting, or preventing obesity | Research & Business Foundation Sungkyunkwan University (KR) | 2018-01-30 | — | — | US | disclosed |
| US-20170087126-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVER SITY (KR) | 2017-03-30 | — | — | US | disclosed |
| US-9549908-B2 | Composition for inducing differentiation into beige and brown adipocytes and method of inducing the same | Research & Business Foundation Sungkyunkwan University, Ltd. (KR) | 2017-01-24 | — | — | US | disclosed |
| CN-104288133-B | 3,5-diisoamyl thiazolinyl, 2,4, the purposes of 4 '-trihydroxy chalcone and derivant thereof and preparation | TIANJIN UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2016-04-06 | — | — | CN | disclosed |
| EP-1487434-B1 | BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER ACTIVITY COMPRISING ISOLIQUIRITIGENIN | MEDICAL RES AND EDUCATION TRUS (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20050032882-A1 | Botanical extract compositions and methods of use | ACTIVEPHYTO TECHNOLOGIES LIMITED (GB) | 2005-02-10 | — | — | US | disclosed |
| EP-1487434-A2 | BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER OR PHYTOESTROGENIC ACTIVITY COMPRISING WOGONIN, ISOLIQUIRITIGENIN AND/OR COUMESTROL | The Medical Research and Education Trust (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2004080474-A1 | BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER OR PHYTOESTROGENIC ACTIVITY COMPRISING PRENYL FLAVONOIDS | THE MEDICAL RESEARCH AND EDUCATION TRUST (US) | 2004-09-23 | — | — | WO | disclosed |
| WO-2003075943-A2 | BOTANICAL EXTRACT COMPOSITIONS WITH ANTI-CANCER OR PHYTOESTROGENIC ACTIVITY COMPRISING WOGONIN, ISOLIQUIRITIGENIN AND/OR COUMESTROL | THE MEDICAL RESEARCH AND EDUCATION TRUST (US) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087126-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | FABP4, PLIN1, PRDM7 | CHRNA7 2475/4885TYR 1315/4885CTSL 4664/4885 |
| US-20150374643-A1 | COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME | FABP4, PLIN1, PRDM7 | CHRNA7 2475/4885TYR 1315/4885CTSL 4664/4885 |
| US-20050032882-A1 | Botanical extract compositions and methods of use | CYP19A1, ESR1, GPER1 | CHRNA7 2316/4885TYR 538/4885CTSL 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.