Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292847 | 0.99 | EHMT1 (0.68) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| Water SCHEMBL8341906 | 0.98 | EHMT1 (0.67) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| SCHEMBL9339774 | 0.93 | EHMT1 (0.63) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| SCHEMBL10865966 | 0.87 | EHMT1 (0.74) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| SCHEMBL1920531 | 0.87 | EHMT1 (0.74) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| SCHEMBL9231760 | 0.86 | EHMT1 (0.76) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| SCHEMBL1637468 | 0.86 | EHMT1 (0.76) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| SCHEMBL8671033 | 0.85 | EHMT1 (0.74) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| SCHEMBL8671037 | 0.85 | EHMT1 (0.74) | EHMT1RXFP1ADORA2AADORA2BADORA1 | |
| SCHEMBL2534140 | 0.83 | EHMT1 (0.70) | EHMT1RXFP1ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444196-B1 | AGENT FOR TREATMENT AND PROPHYLAXIS OF ISCHEMIC DISEASE OF HEART OR BRAIN | YAMASA SHOYU KK (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-5270304-A | Therapeutic 2-alkynyl adenosine agent for ischemic diseases of the heart or brain | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0444196-A1 | AGENT FOR TREATMENT AND PROPHYLAXIS OF ISCHEMIC DISEASE OF HEART OR BRAIN | Yamasa Shoyu Kabushiki Kaisha (JP) | 1991-09-04 | — | — | EP | disclosed |