Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | STS | P08842 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933617 | 0.92 | EPHX2 (0.58) | HPGDALDH1A1EPHX2LMNANR1H4 | |
| SCHEMBL13968725 | 0.88 | EPHX2 (0.54) | HPGDEPHX2LMNANR1H4PPARG | |
| SCHEMBL934006 | 0.85 | EPHX2 (0.60) | HPGDALDH1A1EPHX2NR1H4PPARG | |
| SCHEMBL934427 | 0.84 | EPHX2 (0.66) | HPGDEPHX2CNR1 | |
| SCHEMBL933945 | 0.82 | CNR1 (0.76) | HPGDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL26749658 | 0.82 | HPGD (0.76) | HPGDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL934422 | 0.81 | HPGD (0.70) | HPGDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL8269670 | 0.81 | HPGD (0.66) | HPGDALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL17335666 | 0.81 | EPHX2 (0.72) | EPHX2CNR1 | |
| SCHEMBL20152027 | 0.80 | EPHX2 (0.59) | HPGDALDH1A1EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |