Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3678084 | 0.79 | MAOB (0.42) | EGFRERBB2KMT2ANPC1POLB | |
| SCHEMBL9344000 | 0.78 | KMT2A (0.61) | CA2CA1CA9KMT2AMMP1 | |
| SCHEMBL11036282 | 0.77 | KMT2A (0.59) | CA2CA1CA9KMT2AMMP1 | |
| SCHEMBL6466 | 0.76 | EGFR (0.43) | EGFRERBB2IDO1PLCG1CA2 | |
| SCHEMBL9200717 | 0.75 | PLCG1 (0.46) | EGFRERBB2IDO1PLCG1CA2 | |
| SCHEMBL1138688 | 0.75 | PLCG1 (0.46) | EGFRERBB2IDO1PLCG1CA2 | |
| SCHEMBL9000869 | 0.74 | EGFR (0.42) | EGFRERBB2IDO1PLCG1CA2 | |
| Hydrochloric Acid SCHEMBL3616094 | 0.74 | EGFR (0.42) | EGFRERBB2IDO1PLCG1CA2 | |
| SCHEMBL2028261 | 0.71 | PLCG1 (0.43) | EGFRERBB2IDO1PLCG1CA2 | |
| SCHEMBL9629254 | 0.71 | IDO1 (0.43) | EGFRERBB2IDO1PLCG1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378082-B1 | 1-Hydroxy-1,2,4-triazoles | BASF AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0388665-B1 | Substituted N-hydroxypyrazoles and N-hydroxy-triazoles and their use in combatting parasites | BASF AG (DE) | 1994-04-27 | — | — | EP | disclosed |
| EP-0388665-A1 | Substituted N-hydroxypyrazoles and N-hydroxy-triazoles and their use in combatting parasites | BASF Aktiengesellschaft (DE) | 1990-09-26 | — | — | EP | disclosed |
| EP-0378082-A1 | 1-Hydroxy-1,2,4-triazoles | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |