Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920290 | 0.86 | PARP15 (0.50) | SIGMAR1 | |
| SCHEMBL5567574 | 0.83 | SIGMAR1 (0.51) | SIGMAR1 | |
| SCHEMBL7364335 | 0.81 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL7362469 | 0.81 | SIGMAR1 (0.71) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7356651 | 0.79 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL7362689 | 0.79 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL7396474 | 0.78 | SIGMAR1 (0.66) | SIGMAR1 | |
| SCHEMBL14163902 | 0.77 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL7362580 | 0.76 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL5563456 | 0.76 | TDP1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296479-A | Treating physiological or drug-induced psychosis or dyskinesia | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-03-22 | — | — | US | disclosed |
| US-5266572-A | Antipsychotic 1-cycloalkylpiperidines | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-11-30 | — | — | US | disclosed |
| US-5243048-A | Treatment of drug-induced or physiological psychosis or dyskinesia; side effect reduction | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| US-5109002-A | ANTIPSYCHOTIC 1-CYCLOALKYLPIPERIDINES | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-04-28 | — | — | US | disclosed |