Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343286 | 0.87 | KDM4E (0.44) | SLC6A4ALDH1A1HTR2AKCNH2 | |
| SCHEMBL10548072 | 0.85 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3ALDH1A1LMNA | |
| SCHEMBL10543538 | 0.85 | MAPT (0.38) | SLC6A4SLC6A2SLC6A3HSPB1ALDH1A1 | |
| SCHEMBL10546165 | 0.85 | L3MBTL1 (0.41) | SLC6A4SLC6A2SLC6A3ALDH1A1LMNA | |
| SCHEMBL1554311 | 0.85 | LTA4H (0.41) | SLC6A4SLC6A2SLC6A3LMNAL3MBTL1 | |
| SCHEMBL9343557 | 0.85 | HTR2A (0.44) | SLC6A4LMNAHTR2AKCNH2SOS1 | |
| SCHEMBL9338779 | 0.81 | HTR2A (0.39) | SLC6A4HSPB1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10547411 | 0.81 | CACNA1C (0.47) | SLC6A4SLC6A2SLC6A3ALDH1A1LMNA | |
| SCHEMBL10544719 | 0.80 | SLC6A2 (0.43) | SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL10546868 | 0.78 | SLC6A2 (0.42) | SLC6A4SLC6A2SLC6A3HSPB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045566-A | Phenyl or naphthyl substituted | ICI AMERICAS INC. (US) | 1991-09-03 | — | — | US | claimed |
| EP-0317265-B1 | Novel imidate insecticides | ZENECA INC (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5089623-A | Certain imidate insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| US-5070210-A | Novel ketenimines as intermediates for insecticides | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5064846-A | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1991-11-12 | — | — | US | disclosed |
| US-5045566-A | Phenyl or naphthyl substituted | ICI AMERICAS INC. (US) | 1991-09-03 | — | — | US | disclosed |
| US-4994473-A | For plants | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| US-4994488-A | Controlling Lepidoptera | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0317265-A2 | Novel imidate insecticides | ZENECA INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |
| US-4602912-A | SYNTHETIC PYRETHROID;FOR KERATINOUS MATERIAL | CIBA-GEIBY CORPORATION (US) | 1986-07-29 | — | — | US | disclosed |
| US-4599362-A | 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives | MITSUITOATSU CHEMICALS, INC. (JP) | 1986-07-08 | — | — | US | disclosed |
| US-4503100-A | 5-PHENYLCARBAMOYLBARBITURIC ACID AND SYNTHETIC PYRETHROID | CIBA-GEIGY CORPORATION (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0001566-B1 | CYCLOBUTANECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0001566-A2 | Cyclobutanecarboxylic acid derivatives, processes for their preparation and their use as insecticides | BAYER AG (DE) | 1979-05-02 | — | — | EP | disclosed |