Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | DHFR | P00374 | 3/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386872 | 1.00 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6308177 | 1.00 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27584197 | 0.93 | L3MBTL1 (0.65) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9471635 | 0.91 | FOLH1 (0.58) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9471642 | 0.90 | FOLH1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16509378 | 0.89 | L3MBTL1 (0.61) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11631569 | 0.88 | L3MBTL1 (0.67) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11631574 | 0.88 | L3MBTL1 (0.67) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9383025 | 0.87 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9540673 | 0.87 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344932-A | N-(pyrrolo(2,3-d)pyrimidin-3-ylacyl)-glutamic acid derivatives | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5248775-A | Pyrrolo(2,3-d)pyrimidines | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0432677-A1 | N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4883799-A | N-(4-(1-hydroxy-3-(5,6,7,8-tetrahydropyrido(2,3,-d)-pyrimidin-6-yl)prop-2-yl)benzoyl)glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-11-28 | — | — | US | disclosed |