Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | DHFR | P00374 | 3/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540678 | 1.00 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL27584197 | 0.93 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL16509378 | 0.89 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11631574 | 0.88 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL11631569 | 0.88 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9383025 | 0.87 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9340435 | 0.87 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9383029 | 0.87 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9386872 | 0.87 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28410876 | 0.87 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013102-A1 | DEAZAAMINOPTERINS | SOUTHERN RESEARCH INSTITUTE (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5077404-A | Cyclized 5,10-dideazaaminopterin compounds | SRI INTERNATIONAL | 1991-12-31 | — | — | US | disclosed |