Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340452 | 0.85 | NR3C1 (0.42) | NR3C1MEN1KMT2AHTR2AIDO1 | |
| SCHEMBL9043743 | 0.76 | CYP3A4 (0.54) | — | |
| SCHEMBL9341483 | 0.74 | MEN1 (0.45) | MEN1KMT2AHTR2ANFE2L2NPC1 | |
| SCHEMBL9340512 | 0.69 | HTR2A (0.38) | NR3C1MEN1KMT2AHTR2ANFE2L2 | |
| SCHEMBL7668721 | 0.68 | IDO1 (0.52) | IDO1SMN1; SMN2TP53MAOB | |
| SCHEMBL531512 | 0.65 | KIF11 (0.47) | GAAKIF11 | |
| SCHEMBL1507033 | 0.64 | KCNN4 (0.43) | MEN1KMT2AGAA | |
| SCHEMBL10398190 | 0.64 | KCNN4 (0.40) | IDO1NFE2L2GAA | |
| SCHEMBL29727285 | 0.64 | KCNN4 (0.43) | MEN1KMT2AGAA | |
| SCHEMBL14398864 | 0.64 | KCNN4 (0.43) | MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312815-A | Fungicidal (+)-2-(2,4-difluorophenyl)-3-methyl-1-(1H-1,2,4-triazol-1-yl)3-(6-(1H-1,2,4-triazol-1-yl)pyridazin-3-ylthio) butan-2-ol | ROUSSEL MORISHITA CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0552974-A1 | A 1-aryl-2-(1H-1,2-4-triazol-1-yl) ethanol derivative and antifungal compositions containing that derivative | ROUSSEL MORISHITA Co., Ltd. (JP) | 1993-07-28 | — | — | EP | disclosed |