SCHEMBL9340481

SCHEMBL9340481

CCC(C)c1ccc(-c2ccc(C(C)C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TSHR P16473 2/20 0.43
CYP2C9 P11712 1/20 0.43
USP2 O75604 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KIF11 P52732 1/20 0.41
GRIA4 P48058 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
FFAR1 O14842 1/20 0.40
PTPN5 P54829 1/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11602428 0.93 ALDH1A1 (0.47) ALDH1A1TSHRCYP2C9USP2GAA
SCHEMBL9339775 0.93 ALDH1A1 (0.47) ALDH1A1TSHRCYP2C9USP2GAA
SCHEMBL16542111 0.90 CYP2C9 (0.41) ALDH1A1TSHRCYP2C9USP2GAA
SCHEMBL14592718 0.90 CYP2C9 (0.41) ALDH1A1TSHRCYP2C9USP2GAA
Hydrogen Peroxide SCHEMBL9339800 0.88 ALDH1A1 (0.53) ALDH1A1TSHRCYP2C9USP2GAA
Hydrogen Peroxide SCHEMBL9344179 0.88 ALDH1A1 (0.53) ALDH1A1TSHRCYP2C9USP2GAA
SCHEMBL23456214 0.86 GRIA4 (0.53) ALDH1A1TSHRCYP2C9USP2GAA
SCHEMBL25671392 0.86 ADRB2 (0.46) ALDH1A1TSHRCYP2C9USP2GAA
SCHEMBL12622293 0.85 ALDH1A1 (0.40) ALDH1A1TSHRCYP2C9USP2GAA
SCHEMBL598140 0.84 ALDH1A1 (0.52) ALDH1A1TSHRCYP2C9USP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5338887-A Process for the preparation of dihydroperoxyalkyl polyphenyls and dihydroxy polyphenyls THE DOW CHEMICAL COMPANY (US) 1994-08-16 US disclosed