Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547261 | 0.88 | TSHR (0.42) | ALDH1A1L3MBTL1LMNASLC6A2SLC6A4 | |
| SCHEMBL3755349 | 0.83 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1LMNASLC6A2SLC6A4 | |
| SCHEMBL10546544 | 0.83 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3HTR1AMAPT | |
| SCHEMBL9361407 | 0.77 | CYP1A2 (0.42) | ALDH1A1L3MBTL1LMNASLC6A2SLC6A4 | |
| SCHEMBL6136698 | 0.76 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNASLC6A2SLC6A4 | |
| SCHEMBL10547079 | 0.76 | RHEB (0.45) | ALDH1A1SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL6290676 | 0.75 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1LMNASLC6A2SLC6A4 | |
| SCHEMBL6290609 | 0.73 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNASLC6A2SLC6A4 | |
| SCHEMBL6293775 | 0.73 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNASLC6A2SLC6A4 | |
| SCHEMBL6289924 | 0.73 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317265-B1 | Novel imidate insecticides | ZENECA INC (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5089623-A | Certain imidate insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| US-5070210-A | Novel ketenimines as intermediates for insecticides | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5045566-A | Phenyl or naphthyl substituted | ICI AMERICAS INC. (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0317265-A2 | Novel imidate insecticides | ZENECA INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |
| US-4599362-A | 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives | MITSUITOATSU CHEMICALS, INC. (JP) | 1986-07-08 | — | — | US | disclosed |