Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16635252 | 0.83 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 | |
| SCHEMBL9340499 | 0.76 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 | |
| SCHEMBL6290676 | 0.75 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 | |
| SCHEMBL22966254 | 0.75 | HSPB1 (0.47) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 | |
| SCHEMBL6293775 | 0.73 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 | |
| SCHEMBL6289924 | 0.73 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 | |
| SCHEMBL6293841 | 0.73 | L3MBTL1 (0.58) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 | |
| SCHEMBL6290609 | 0.73 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 | |
| SCHEMBL2094827 | 0.72 | CA1 (0.46) | ALDH1A1L3MBTL1LMNAMAPK1TDP1 | |
| SCHEMBL11334317 | 0.72 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1LMNAHTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115695-B1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(N+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO CO (US) | 2005-06-01 | — | — | EP | disclosed |