Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487930 | 0.96 | TRPM8 (0.55) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL18428166 | 0.92 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL8548065 | 0.91 | TRPM8 (0.59) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL4877337 | 0.90 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL31652833 | 0.84 | TRPM8 (0.49) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL9080881 | 0.84 | TRPM8 (0.60) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| Formamide SCHEMBL28146157 | 0.82 | TRPM8 (0.50) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| Formamide SCHEMBL28226962 | 0.81 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL28128278 | 0.81 | TRPM8 (0.48) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 | |
| SCHEMBL27969261 | 0.76 | TRPA1 (0.47) | TRPM8TRPA1EPHX1ALDH1A1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298628-A | Catalytical reduction with hydrogen and cylcizing in presence of hydrogenation catalyst, etherification | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-03-29 | — | — | US | claimed |