Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341400 | 0.91 | PPARG (0.50) | ACHEPPARGAGTR1 | |
| SCHEMBL9337468 | 0.88 | ACHE (0.47) | ACHEPPARG | |
| SCHEMBL9337535 | 0.86 | ACHE (0.48) | ACHEPPARG | |
| SCHEMBL9341332 | 0.86 | ACHE (0.49) | ACHEPPARGAGTR1 | |
| SCHEMBL9337738 | 0.85 | PPARG (0.56) | ACHEPPARGAGTR1 | |
| SCHEMBL9337252 | 0.85 | PPARG (0.48) | ACHEPPARGAGTR1 | |
| SCHEMBL9337279 | 0.85 | PPARG (0.46) | ACHEPPARG | |
| SCHEMBL9336755 | 0.84 | PPARG (0.58) | ACHEPPARGAGTR1 | |
| SCHEMBL9340918 | 0.84 | PPARG (0.46) | ACHEPPARGAGTR1 | |
| SCHEMBL9339221 | 0.83 | PPARG (0.46) | ACHEPPARGAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332750-A | Treatment of hypertension, aldosteronism, cardiac insufficienc y | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-07-26 | — | — | US | disclosed |