Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337468 | 0.90 | ACHE (0.47) | PPARGACHEKDM4E | |
| SCHEMBL9339237 | 0.90 | PPARG (0.46) | PPARGACHEAGTR1 | |
| SCHEMBL9337252 | 0.89 | PPARG (0.48) | PPARGACHEAGTR1 | |
| SCHEMBL9337279 | 0.89 | PPARG (0.46) | PPARGACHE | |
| SCHEMBL9336987 | 0.87 | ACHE (0.46) | PPARGACHE | |
| SCHEMBL9337565 | 0.87 | PPARG (0.46) | PPARGACHEAGTR1 | |
| SCHEMBL9337392 | 0.85 | PPARG (0.45) | PPARGACHEAGTR1 | |
| SCHEMBL9340760 | 0.84 | ACHE (0.49) | PPARGACHEAGTR1 | |
| SCHEMBL9341400 | 0.84 | PPARG (0.50) | PPARGACHEAGTR1 | |
| SCHEMBL9341332 | 0.83 | ACHE (0.49) | PPARGACHEAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332750-A | Treatment of hypertension, aldosteronism, cardiac insufficienc y | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-07-26 | — | — | US | disclosed |