SCHEMBL9340775

SCHEMBL9340775

CCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.43
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ALDH1A1 P00352 8/20 0.36
MAPT P10636 8/20 0.36
KDM4E B2RXH2 5/20 0.36
TDP1 Q9NUW8 1/20 0.35
TP53 P04637 3/20 0.34
RORC P51449 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
TSHR P16473 4/20 0.33
GAA P10253 3/20 0.33
LMNA P02545 3/20 0.33
ATM Q13315 3/20 0.33
THRB P10828 2/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29807700 1.00 HSPA5 (0.43) HSPA5NPC1RAB9AALDH1A1MAPT
SCHEMBL14423818 0.91 NPC1 (0.37) HSPA5NPC1RAB9AALDH1A1MAPT
SCHEMBL27467453 0.89 NPC1 (0.38) HSPA5NPC1RAB9AALDH1A1MAPT
SCHEMBL19884685 0.89 NPC1 (0.38) HSPA5NPC1RAB9AALDH1A1MAPT
SCHEMBL6837010 0.89 NPC1 (0.38) HSPA5NPC1RAB9AALDH1A1MAPT
SCHEMBL6908032 0.89 NPC1 (0.36) NPC1RAB9AALDH1A1MAPTKDM4E
SCHEMBL30240899 0.88 NPC1 (0.37) NPC1RAB9AALDH1A1MAPTKDM4E
SCHEMBL77250 0.88 NPC1 (0.37) NPC1RAB9AALDH1A1MAPTKDM4E
SCHEMBL16096507 0.87 NPC1 (0.36) NPC1RAB9AALDH1A1MAPTKDM4E
SCHEMBL4647349 0.87 PTGS2 (0.35) NPC1RAB9AALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3936905-B1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD (TH) 2026-04-29 EP claimed
CN-119285886-A Method for producing optical material, and polymerizable composition for optical material 三井化学株式会社 2025-01-10 CN claimed
CN-113614581-B Method for producing optical material, and polymerizable composition for optical material 三井化学株式会社 2024-10-25 CN claimed
EP-3483219-B1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD (TH) 2024-08-14 EP claimed
CN-113045885-B Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2023-03-21 CN claimed
CN-114891337-A Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2022-08-12 CN claimed
CN-114891336-A Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2022-08-12 CN claimed
CN-114525027-A Transparent plastic base material and plastic lens 豪雅镜片泰国有限公司 2022-05-24 CN claimed
US-20220153963-A1 METHOD OF PRODUCING OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2022-05-19 US claimed
EP-3951443-A1 METHOD FOR PRODUCING OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2022-02-09 EP claimed
CN-111732831-A Transparent plastic substrate and plastic lens 豪雅镜片泰国有限公司 2020-10-02 CN claimed
US-10745539-B2 Transparent plastic substrate and plastic lens HOYA LENS THAILAND LTD. (TH) 2020-08-18 US claimed
EP-3483220-B1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD (TH) 2020-08-05 EP claimed
EP-3483220-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS Hoya Lens Thailand Ltd. (TH) 2019-05-15 EP claimed
EP-3483219-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS Hoya Lens Thailand Ltd. (TH) 2019-05-15 EP claimed
US-20190119467-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD. (TH) 2019-04-25 US claimed
US-20180362731-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD. (TH) 2018-12-20 US claimed
US-20180362730-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD. (TH) 2018-12-20 US claimed
EP-3056545-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS Hoya Lens Thailand Ltd. (TH) 2016-08-17 EP claimed
US-20160215121-A1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD. (TH) 2016-07-28 US claimed