Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241717 | 0.89 | LMNA (0.62) | NPC1RAB9ALMNAALDH1A1HIF1A | |
| SCHEMBL29046140 | 0.88 | NPC1 (0.60) | NPC1RAB9ALMNAALDH1A1HIF1A | |
| Methane SCHEMBL27503343 | 0.88 | LMNA (0.60) | NPC1RAB9ALMNAALDH1A1HIF1A | |
| SCHEMBL11621092 | 0.86 | NPC1 (0.59) | NPC1RAB9ALMNAALDH1A1POLB | |
| SCHEMBL9342923 | 0.85 | NPC1 (0.61) | NPC1RAB9ALMNAALDH1A1HTT | |
| SCHEMBL28680438 | 0.84 | NPC1 (0.56) | NPC1RAB9ALMNAALDH1A1HIF1A | |
| SCHEMBL5846814 | 0.84 | NPC1 (0.56) | NPC1RAB9ALMNAALDH1A1HIF1A | |
| SCHEMBL7032725 | 0.84 | NPC1 (0.46) | NPC1RAB9ALMNAALDH1A1ALOX12 | |
| SCHEMBL20335164 | 0.83 | NPC1 (0.55) | NPC1RAB9ALMNAALDH1A1HIF1A | |
| SCHEMBL20497195 | 0.83 | NPC1 (0.55) | NPC1RAB9ALMNAALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4187679-A | — | — | None | — | — | JP | disclosed |
| US-20180195000-A1 | SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY | 2018-07-12 | — | — | US | disclosed |
| US-8980525-B2 | Chemically amplified positive resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20130026044-A1 | CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-01-31 | — | — | US | disclosed |
| EP-2551722-A1 | Chemically amplified positive resist composition and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2013-01-30 | — | — | EP | disclosed |
| CN-1031340-C | Process for preparing substituted 2H-benzotriazole liquid mixtures | CIBA GEIGY AG (CH) | 1996-03-20 | — | — | CN | disclosed |
| CN-1106934-A | Liquid substituted 2H-benzotriazole mixtures | CIBA GEIGY AG (CH) | 1995-08-16 | — | — | CN | disclosed |
| EP-0337942-B1 | Liquid substituted 2H-benzotriazole mixtures | CIBA GEIGY AG (CH) | 1994-07-06 | — | — | EP | disclosed |
| JP-H04187679-A | PREPARATION OF 2-(2-HYDROXYPHENYL)BENZOTRIAZOLE DERIVATIVE | SHIPURO KASEI KK | 1992-07-06 | — | — | JP | disclosed |
| CN-1037337-A | Substituted 2H-benzotriazole liquid mixtures | CIBA GEIGY AG (CH) | 1989-11-22 | — | — | CN | disclosed |
| EP-0337942-A1 | Liquid substituted 2H-benzotriazole mixtures | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |
| US-4128559-A | ANTIDEPRESSANT | EASTMAN KODAK COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4127586-A | HYDROXYPHENYL BENZOTRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1978-11-28 | — | — | US | disclosed |
| US-4041011-A | FOR POLYMERS | EASTMAN KODAK COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
| US-3936418-A | Benzotriazole ortho-ester ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180195000-A1 | SUBSTITUTED BENZOTRIAZOLE PHENOLATE SALTS AND ANTIOXIDANT COMPOSITIONS FORMED THEREFROM | COMT, OGFOD1, TYR | NPC1 4227/4885RAB9A 4875/4885LMNA 3383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.