SCHEMBL93418

SCHEMBL93418

COC(=O)c1cc2ccc(OCc3ccccc3)cc2oc1=O

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 16/20 0.80
MAOA P21397 11/20 0.78
SLC16A3 O15427 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17704689 0.90 MAOB (0.70) MAOBMAOASLC16A3
SCHEMBL93300 0.89 MAOB (0.85) MAOBMAOASLC16A3
SCHEMBL17704680 0.89 MAOB (0.79) MAOBMAOASLC16A3
SCHEMBL5109572 0.89 MAOB (0.80) MAOBMAOASLC16A3
SCHEMBL22148003 0.89 MAOB (1.00) MAOBMAOASLC16A3
SCHEMBL17704686 0.89 MAOB (0.79) MAOBMAOASLC16A3
SCHEMBL17704683 0.88 MAOB (1.00) MAOBMAOASLC16A3
SCHEMBL93260 0.88 SLC16A3 (1.00) MAOBMAOASLC16A3
SCHEMBL30023219 0.86 SLC16A3 (0.82) MAOBMAOASLC16A3
SCHEMBL1067965 0.85 MAOA (0.64) MAOBMAOASLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060178405-A1 Benzopyran compounds, process for preparing the same and their use SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2006-08-10 US claimed
CN-1244573-C Benzofuran category compound, its preparing method and usage SHANGHAI MEDICATION INST CHINE (CN) 2006-03-08 CN claimed
EP-1598345-A1 BENZOPYRAN COMPOUNDS, PROCESS FOR PREPARING THE SAME AND THEIR USE SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2005-11-23 EP claimed
CN-1445222-A Benzofuran category compound, its preparing method and usage SHANGHAI MEDICATION INST CHINE (CN) 2003-10-01 CN claimed
EP-2611912-B1 NOVEL MONOOXYGENASE VARIANTS BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) 2016-11-02 EP disclosed
EP-2611912-B1 NOVEL MONOOXYGENASE VARIANTS BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) 2016-11-02 EP disclosed
WO-2012028709-A2 NOVEL MONOOXYGENASE VARIANTS B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (DE) 2012-03-08 WO disclosed
EP-2426198-A1 Cytochrome P450 monooxygenase variants B.R.A.I.N. Biotechnology Research And Information Network AG (DE) 2012-03-07 EP disclosed
EP-2426198-A1 Cytochrome P450 monooxygenase variants B.R.A.I.N. Biotechnology Research And Information Network AG (DE) 2012-03-07 EP disclosed
US-7456205-B2 Benzopyran compounds, process for preparing the same and their use SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2008-11-25 US disclosed
US-7456205-B2 Benzopyran compounds, process for preparing the same and their use SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2008-11-25 US disclosed
US-7456205-B2 Benzopyran compounds, process for preparing the same and their use SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2008-11-25 US disclosed
US-20060178405-A1 Benzopyran compounds, process for preparing the same and their use SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2006-08-10 US disclosed
CN-1244573-C Benzofuran category compound, its preparing method and usage SHANGHAI MEDICATION INST CHINE (CN) 2006-03-08 CN disclosed
EP-1598345-A1 BENZOPYRAN COMPOUNDS, PROCESS FOR PREPARING THE SAME AND THEIR USE SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2005-11-23 EP disclosed
CN-1445222-A Benzofuran category compound, its preparing method and usage SHANGHAI MEDICATION INST CHINE (CN) 2003-10-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178405-A1 Benzopyran compounds, process for preparing the same and their use SLC5A2, CYP2D6, IAPP MAOB 804/4885MAOA 1404/4885SLC16A3 2784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.