Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 10/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | STK3 | Q13188 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20527932 | 0.83 | PIM1 (0.48) | PIM1PIM2GSK3APIM3RPS6KA3 | |
| SCHEMBL9748506 | 0.83 | PIM1 (0.38) | PIM1PIM2GSK3APIM3RPS6KA3 | |
| SCHEMBL9715578 | 0.81 | KDM4E (0.39) | PIM1PIM2GSK3APIM3RPS6KA3 | |
| SCHEMBL10623503 | 0.81 | KDM4E (0.35) | PIM1PIM2GSK3APIM3DRD3 | |
| SCHEMBL10620783 | 0.81 | HPGD (0.35) | PIM1PIM2GSK3APIM3DRD3 | |
| SCHEMBL11096126 | 0.81 | DRD3 (0.39) | PIM1GSK3APIM3RPS6KA3DYRK1A | |
| SCHEMBL10427396 | 0.80 | CCR3 (0.37) | PIM1PIM2GSK3APIM3KDM4E | |
| SCHEMBL9151598 | 0.80 | GSK3B (0.44) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL9748573 | 0.79 | PIM1 (0.36) | PIM1PIM2GSK3APIM3DRD3 | |
| SCHEMBL10553019 | 0.78 | PIM1 (0.35) | PIM1PIM2GSK3APIM3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351889-B1 | Process for the preparation of a quinoline carboxylic acid | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1994-06-29 | — | — | EP | disclosed |
| US-5294712-A | Process for the preparation of quinoline carboxylic acids | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1994-03-15 | — | — | US | disclosed |
| US-5284950-A | Process for the preparation of quinoline carboxyolic acids | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1994-02-08 | — | — | US | disclosed |
| EP-0249620-B1 | PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACIDS | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-11-19 | — | — | EP | disclosed |
| US-4981966-A | Process for the preparation of quinoline carboxylic acids | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1991-01-01 | — | — | US | disclosed |
| EP-0250535-B1 | NORFLOXACIN INTERMEDIATE | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1990-05-30 | — | — | EP | disclosed |
| EP-0351889-A1 | Process for the preparation of a quinoline carboxylic acid | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1990-01-24 | — | — | EP | disclosed |
| US-4803274-A | Norfloxacin intermediate | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1989-02-07 | — | — | US | disclosed |
| EP-0250535-A1 | NORFLOXACIN INTERMEDIATE. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1988-01-07 | — | — | EP | disclosed |
| EP-0249620-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACIDS. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1987-12-23 | — | — | EP | disclosed |
| WO-1987003587-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACIDS | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1987-06-18 | — | — | WO | disclosed |
| WO-1987003595-A1 | NORFLOXACIN INTERMEDIATE | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1987-06-18 | — | — | WO | disclosed |