Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 8/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341876 | 0.79 | PIM1 (0.50) | PIM1PIM2GSK3APIM3LMNA | |
| SCHEMBL10553019 | 0.77 | PIM1 (0.35) | PIM1PIM2GSK3APIM3LMNA | |
| SCHEMBL9748506 | 0.77 | PIM1 (0.38) | PIM1PIM2GSK3APIM3LMNA | |
| SCHEMBL20527932 | 0.77 | PIM1 (0.48) | PIM1PIM2GSK3APIM3LMNA | |
| SCHEMBL9715578 | 0.76 | KDM4E (0.39) | PIM1PIM2GSK3APIM3LMNA | |
| SCHEMBL10427396 | 0.75 | CCR3 (0.37) | PIM1PIM2GSK3APIM3LMNA | |
| SCHEMBL9163650 | 0.73 | ALDH1A1 (0.38) | PIM1LMNAPOLBHPGDTAAR1 | |
| SCHEMBL10744402 | 0.68 | PIM1 (0.37) | PIM1PIM2GSK3APIM3LMNA | |
| SCHEMBL9748566 | 0.68 | KMT2A (0.52) | PIM1PIM2GSK3APIM3LMNA | |
| SCHEMBL10751688 | 0.68 | PIM1 (0.38) | PIM1PIM2GSK3APIM3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248072-B1 | AMIFLOXACINE INTERMEDIATE | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-03-18 | — | — | EP | disclosed |
| US-4871849-A | 6-FLUORO-7-(PIPERAZINYL OR 4-METHYLPIPERAZINYL) SUBSTITUTED AN TIBACTERIAL AGENTS; NOVEL 3,4-O-BORON DERIVATIVE INTERMEDIATES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1989-10-03 | — | — | US | disclosed |
| US-4806645-A | Boric anhydrides of 6-fluoro-7-chloro-1-methylamino-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1989-02-21 | — | — | US | disclosed |
| EP-0248876-A1 | PROCESS FOR THE PREPARATION OF 1-METHYLAMINO-QUINOLINE-CARBOXYLIC ACID DERIVATIVES. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1987-12-16 | — | — | EP | disclosed |
| EP-0248072-A1 | AMIFLOXACINE INTERMEDIATE. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1987-12-09 | — | — | EP | disclosed |
| WO-1987003594-A1 | AMIFLOXACINE INTERMEDIATE | CHINOIN GYÓGYSZERRÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1987-06-18 | — | — | WO | disclosed |
| WO-1987003586-A1 | PROCESS FOR THE PREPARATION OF 1-METHYLAMINO-QUINOLINE-CARBOXYLIC ACID DERIVATIVES | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1987-06-18 | — | — | WO | disclosed |