Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342014 | 0.89 | MAOB (0.51) | SMN1; SMN2MAPTLMNAHTTNPC1 | |
| SCHEMBL9342747 | 0.89 | AKR1C3 (0.44) | BCHESMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL9338406 | 0.87 | BCL2 (0.43) | BCHESMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL10498739 | 0.84 | RARB (0.53) | SMN1; SMN2MAPTNPC1RAB9AKDM4E | |
| SCHEMBL9341575 | 0.82 | MAOB (0.46) | SMN1; SMN2MAPTLMNAHTTNPC1 | |
| SCHEMBL9338384 | 0.81 | MAOB (0.51) | SMN1; SMN2MAPTLMNAHTTNPC1 | |
| SCHEMBL9342772 | 0.79 | THRA (0.44) | SMN1; SMN2LMNAMAOB | |
| SCHEMBL9342270 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTLMNAHTTNPC1 | |
| SCHEMBL9338105 | 0.78 | CYP2A6 (0.54) | SMN1; SMN2MAPTLMNAHTTNPC1 | |
| SCHEMBL9341461 | 0.78 | PLA2G1B (0.47) | TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |