Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342747 | 0.90 | AKR1C3 (0.44) | BCL2BCHEPTGS2AKR1C3SMN1; SMN2 | |
| SCHEMBL9342248 | 0.87 | BCHE (0.44) | BCL2BCHEPTGS2SMN1; SMN2CASP3 | |
| SCHEMBL9337818 | 0.86 | HDAC4 (0.45) | BCL2PTGS2SMN1; SMN2PTGS1NPC1 | |
| SCHEMBL9779017 | 0.83 | MAOB (0.48) | RELAPTGS2SMN1; SMN2CASP3SENP7 | |
| SCHEMBL9338665 | 0.83 | SLC6A19 (0.51) | PLAAT5PLAAT4RELASMN1; SMN2MAPT | |
| SCHEMBL9338586 | 0.82 | NPSR1 (0.48) | PTGS2SMN1; SMN2PTGS1NPC1MAPT | |
| SCHEMBL9338680 | 0.81 | HDAC4 (0.39) | PTGS2SMN1; SMN2PTGS1NPC1MAPT | |
| SCHEMBL9339939 | 0.80 | MAOB (0.54) | RELABCHE | |
| SCHEMBL9338013 | 0.80 | PTGS2 (0.44) | PTGS2SMN1; SMN2PTGS1NPC1MAPT | |
| SCHEMBL9339925 | 0.80 | HDAC4 (0.41) | SMN1; SMN2CASP3SENP7NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |