Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYB | P10242 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543444 | 0.82 | MYB (0.70) | MYBMAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL8542128 | 0.72 | MYB (1.00) | MYBMAPTLMNAMEN1KMT2A | |
| SCHEMBL8543812 | 0.72 | MEN1 (0.67) | MYBMAPTLMNAMEN1KMT2A | |
| SCHEMBL8541683 | 0.72 | MYB (0.67) | MYBMAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL9343227 | 0.71 | MYB (0.70) | MYBMAPTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL8541677 | 0.71 | MYB (0.66) | MYBMAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL8810542 | 0.69 | MYB (0.74) | MYBMAPTLMNAMEN1KMT2A | |
| SCHEMBL10275382 | 0.69 | MYB (0.74) | MYBMAPTLMNAMEN1KMT2A | |
| SCHEMBL10275379 | 0.69 | MYB (0.74) | MYBMAPTLMNAMEN1KMT2A | |
| SCHEMBL8813293 | 0.68 | MYB (0.55) | MYBMAPTHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281619-A | Administering naphtho(1,2-B)pyran derivatives | ELI LILLY AND COMPANY (US) | 1994-01-25 | — | — | US | disclosed |