Triphenylene

Triphenylene

SCHEMBL9343142

O=C=NC(N=C=O)N=C=O.c1ccc2c(c1)c1ccccc1c1ccccc21

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP1A2 P05177 2/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
HSP90AA1 P07900 1/20 0.33
HPRT1 P00492 1/20 0.32
ALOX5 P09917 1/20 0.31
PAX8 Q06710 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
TSHR P16473 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP3A4 P08684 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
TNKS O95271 1/20 0.30
LMNA P02545 1/20 0.30
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27632953 0.82 ALDH1A1 (0.45) HSD17B10ALDH1A1CYP1A2THRBSMN1; SMN2
Toluene SCHEMBL28268114 0.78 LMNA (0.50) ALDH1A1HPGDTSHRSMN1; SMN2TDP1
SCHEMBL1978494 0.76 TSHR (0.33) TSHR
Triphenylene SCHEMBL5315668 0.73
SCHEMBL1493064 0.73
SCHEMBL1142114 0.73 TSHR (0.31) TSHR
SCHEMBL1493001 0.69 CYP3A4 (0.31) ALDH1A1CYP1A2CYP3A4
SCHEMBL3981386 0.68 ESR1 (0.31) CYP3A4
SCHEMBL8167800 0.68 ALDH1A1 (0.48) HSD17B10ALDH1A1CYP1A2HPGDTSHR
Triphenylene SCHEMBL9251630 0.67 HPRT1 (0.40) HSD17B10ALDH1A1CYP1A2THRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5367036-A Polyether or ester urethane copolymer blends for heat resistance THE YOKOHAMA RUBBER CO., LTD. (JP) 1994-11-22 US claimed
EP-0540950-A2 Moisture-curable urethane-based sealing composition THE YOKOHAMA RUBBER CO., LTD. (JP) 1993-05-12 EP claimed
EP-0232496-B1 METHOD FOR CURING AROMATIC POLYTHIOETHER SULFONE ASAHI GLASS COMPANY LTD. (JP) 1992-02-26 EP disclosed
US-4736000-A MIXING WITH EPOXIDES, ISOCYANATES, MALEIMIDES, AMINO RESINS, METAL ACETYLACETONATES OR METAL HALIDES ASAHI GLASS COMPANY LTD. (JP) 1988-04-05 US disclosed
EP-0232496-A2 Method for curing aromatic polythioether sulfone ASAHI GLASS COMPANY LTD. (JP) 1987-08-19 EP disclosed
US-4357401-A Macromolecular material of ionic conduction L'ETAT FRANCAIS REPRESENTE PAR LE DELEGUE GENERAL POUR L'ARMEMENT (FR) 1982-11-02 US disclosed