Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276184 | 0.87 | MAPK1 (0.49) | MAPK1L3MBTL1KDM4EPOLBPKM | |
| SCHEMBL9345658 | 0.85 | MAPK1 (0.61) | MAPK1L3MBTL1KDM4EPOLBPKM | |
| SCHEMBL9345683 | 0.85 | MAPK1 (0.53) | MAPK1L3MBTL1KDM4EPOLBPKM | |
| SCHEMBL9302975 | 0.84 | POLB (0.60) | L3MBTL1KDM4EPOLBPKMMAPT | |
| SCHEMBL9302968 | 0.84 | POLB (0.60) | L3MBTL1KDM4EPOLBPKMMAPT | |
| SCHEMBL9302681 | 0.80 | HRH3 (0.56) | MAPK1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL29637478 | 0.80 | MAPK1 (0.61) | MAPK1L3MBTL1KDM4EPOLBPKM | |
| SCHEMBL1971939 | 0.80 | MAPK1 (0.61) | MAPK1L3MBTL1KDM4EPOLBPKM | |
| SCHEMBL9341797 | 0.79 | JMJD6 (0.43) | KDM4EKMT2AALDH1A1GABRPGABRD | |
| SCHEMBL30876053 | 0.79 | PDCD1 (0.53) | KDM4EKMT2AALDH1A1MEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364873-A | Influencing metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| US-5238948-A | Influence metabolism of collagen or biosynthesis of C1q | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |