Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345683 | 0.88 | MAPK1 (0.53) | MAPK1KDM4EL3MBTL1KMT2ANPC1 | |
| SCHEMBL9343294 | 0.85 | MAPK1 (0.50) | MAPK1KDM4EL3MBTL1KMT2AP4HTM | |
| SCHEMBL9342427 | 0.79 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1KMT2ANPC1 | |
| SCHEMBL9303366 | 0.79 | KMT2A (0.60) | KMT2ANPC1MEN1 | |
| SCHEMBL9304053 | 0.79 | KMT2A (0.60) | KMT2ANPC1MEN1 | |
| SCHEMBL29508473 | 0.77 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1KMT2ANPC1 | |
| SCHEMBL69747 | 0.77 | MAPK1 (1.00) | MAPK1KDM4EL3MBTL1KMT2ANPC1 | |
| SCHEMBL9733449 | 0.76 | CA1 (0.65) | MAPK1KMT2AMEN1 | |
| SCHEMBL9733455 | 0.76 | CA1 (0.65) | MAPK1KMT2AMEN1 | |
| SCHEMBL7276184 | 0.75 | MAPK1 (0.49) | MAPK1KDM4EL3MBTL1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364873-A | Influencing metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| US-5238948-A | Influence metabolism of collagen or biosynthesis of C1q | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |