Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | TPH1 | P17752 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348521 | 0.93 | MEN1 (0.39) | TDP1MEN1ALOX15CYP2C19KMT2A | |
| SCHEMBL9345597 | 0.90 | MEN1 (0.50) | TDP1MEN1ALOX15CYP2C19KMT2A | |
| SCHEMBL9345173 | 0.90 | KMT2A (0.40) | TDP1MEN1ALOX15CYP2C19KMT2A | |
| SCHEMBL9344786 | 0.89 | MEN1 (0.43) | TDP1MEN1ALOX15CYP2C19KMT2A | |
| SCHEMBL9348888 | 0.85 | MEN1 (0.41) | TDP1MEN1ALOX15CYP2C19KMT2A | |
| SCHEMBL9348882 | 0.85 | MEN1 (0.41) | TDP1MEN1ALOX15CYP2C19KMT2A | |
| SCHEMBL9343960 | 0.79 | MEN1 (0.52) | TDP1MEN1ALOX15CYP2C19KMT2A | |
| SCHEMBL9345135 | 0.77 | MEN1 (0.56) | TDP1MEN1ALOX15CYP2C19KMT2A | |
| SCHEMBL21117877 | 0.75 | EPHX2 (0.51) | CYP2C19MAPTALDH1A1LMNASLC6A2 | |
| SCHEMBL2734222 | 0.75 | EPHX2 (0.51) | CYP2C19MAPTALDH1A1LMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321016-A | Epliepsy, central nervous system disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1994-06-14 | — | — | US | disclosed |