Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345173 | 0.91 | KMT2A (0.40) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9343956 | 0.90 | TDP1 (0.40) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9348521 | 0.89 | MEN1 (0.39) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9344811 | 0.83 | MEN1 (0.69) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9348882 | 0.82 | MEN1 (0.41) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9348888 | 0.82 | MEN1 (0.41) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9344786 | 0.81 | MEN1 (0.43) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9212719 | 0.79 | SLC7A5 (0.53) | MEN1ALOX15KMT2AHSD17B10TDP1 | |
| SCHEMBL9344824 | 0.79 | PPARA (0.46) | ALDH1A1HPGDPPARGPPARA | |
| SCHEMBL9343960 | 0.75 | MEN1 (0.52) | MEN1ALOX15CYP2C19KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651758-A1 | PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS | Paris Sciences et Lettres - Quartier Latin (FR) | 2020-05-20 | — | — | EP | disclosed |
| WO-2019012109-A1 | PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2019-01-17 | — | — | WO | disclosed |
| US-5321016-A | Epliepsy, central nervous system disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5162311-A | Treating epilepsy, psychiatric disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1992-11-10 | — | — | US | disclosed |