Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348521 | 0.87 | MEN1 (0.39) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9344811 | 0.85 | MEN1 (0.69) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9345161 | 0.85 | MEN1 (0.56) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL539261 | 0.81 | ROCK2 (0.52) | CYP2C19ALDH1A1ROCK2CYP1A2CYP2C9 | |
| SCHEMBL539262 | 0.81 | ROCK2 (0.52) | CYP2C19ALDH1A1ROCK2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL539617 | 0.80 | ROCK2 (0.51) | CYP2C19ALDH1A1ROCK2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL539618 | 0.80 | ROCK2 (0.51) | CYP2C19ALDH1A1ROCK2CYP1A2CYP2C9 | |
| SCHEMBL9343957 | 0.80 | MEN1 (0.53) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9345165 | 0.80 | MEN1 (0.53) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9343956 | 0.79 | TDP1 (0.40) | MEN1ALOX15CYP2C19KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321016-A | Epliepsy, central nervous system disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5162311-A | Treating epilepsy, psychiatric disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1992-11-10 | — | — | US | disclosed |