Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113930 | 0.93 | IDO1 (0.52) | IDO1RAB9ASMN1; SMN2NPC1NPBWR1 | |
| Alcohol SCHEMBL5309262 | 0.88 | IDO1 (0.48) | IDO1RAB9ASMN1; SMN2NPC1NPBWR1 | |
| SCHEMBL5272879 | 0.84 | PTPN5 (0.41) | IDO1KIF11FFAR1PTPN5RAB9A | |
| SCHEMBL30844144 | 0.83 | IDO1 (0.44) | IDO1RAB9ASMN1; SMN2KDM4ENPC1 | |
| Acetic Acid SCHEMBL29144999 | 0.83 | RXRA (0.47) | IDO1RAB9ASMN1; SMN2KDM4ENPC1 | |
| Benzyl Alcohol SCHEMBL28599336 | 0.82 | TSHR (0.64) | IDO1RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL13524585 | 0.81 | RXRA (0.58) | KIF11MKNK1MKNK2PTPN5ADAMTS4 | |
| Hydrogen Peroxide SCHEMBL9643171 | 0.80 | KIF11 (0.54) | KIF11FFAR1PTPN5RAB9ASMN1; SMN2 | |
| Hydrogen Peroxide SCHEMBL9176615 | 0.80 | KIF11 (0.54) | KIF11FFAR1PTPN5RAB9ASMN1; SMN2 | |
| SCHEMBL679970 | 0.80 | MKNK1 (0.56) | KIF11MKNK1MKNK2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024057020-A1 | ANTI-VIRAL COMPOUNDS | Infex Therapeutics Limited (GB) | 2024-03-21 | — | — | WO | disclosed |
| WO-2018022952-A1 | NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM | PROMERUS, LLC (US) | 2018-02-01 | — | — | WO | disclosed |
| WO-2017117483-A1 | POLYMERS DERIVED FROM NORBORNADIENE AND MALEIC ANHYDRIDE AND USE THEREOF | PROMERUS, LLC (US) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017095829-A2 | PERMANENT DIELECTRIC COMPOSITIONS CONTAINING PHOTOACID GENERATOR AND BASE | PROMERUS, LLC (US) | 2017-06-08 | — | — | WO | disclosed |
| US-7968577-B2 | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-06-28 | — | — | US | disclosed |
| US-7968577-B2 | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-06-28 | — | — | US | disclosed |
| US-20100063051-A1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2010-03-11 | — | — | US | disclosed |
| US-20100063051-A1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2010-03-11 | — | — | US | disclosed |
| US-5338887-A | Process for the preparation of dihydroperoxyalkyl polyphenyls and dihydroxy polyphenyls | THE DOW CHEMICAL COMPANY (US) | 1994-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063051-A1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | NFRKB, NFKB2, NFKBIA | IDO1 2669/4885KIF11 3208/4885MKNK1 713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.