Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344111 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2GPR119HTR2AHTR2C | |
| SCHEMBL7737588 | 0.87 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GAAKDM4EHPGD | |
| SCHEMBL8535967 | 0.87 | BRD4 (0.43) | ALDH1A1SMN1; SMN2GPR119HTR2AHTR2C | |
| SCHEMBL9505686 | 0.83 | OPRM1 (0.41) | ALDH1A1SMN1; SMN2GPR119HTR2AHTR2C | |
| SCHEMBL13998334 | 0.83 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2GPR119HTR2AHTR2C | |
| SCHEMBL11477738 | 0.82 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2KDM4EL3MBTL1BRD4 | |
| SCHEMBL29423728 | 0.80 | MAPT (0.38) | ALDH1A1SMN1; SMN2GPR119HTR2AHTR2C | |
| SCHEMBL22692132 | 0.80 | MAPT (0.38) | ALDH1A1SMN1; SMN2GPR119HTR2AHTR2C | |
| SCHEMBL22692122 | 0.78 | BRD4 (0.39) | ALDH1A1SMN1; SMN2GAAKDM4EHPGD | |
| SCHEMBL29423722 | 0.78 | BRD4 (0.39) | ALDH1A1SMN1; SMN2GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292768-A | Compound effective as cerebral insufficiency improver | SUNTORY LIMITED (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |