Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934355 | 0.84 | EPHX1 (0.52) | EPHX1GRIN2B | |
| SCHEMBL934605 | 0.84 | TAAR1 (0.55) | FOLH1 | |
| SCHEMBL934550 | 0.82 | EPHX1 (0.56) | EPHX1TRPM8CETPAMPD2CHRM2 | |
| SCHEMBL23095166 | 0.81 | CETP (0.48) | CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL26616861 | 0.81 | EPHX1 (0.55) | EPHX1TRPM8CETPAMPD2CHRM2 | |
| SCHEMBL13849933 | 0.80 | CETP (0.58) | CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL13849901 | 0.80 | CETP (0.58) | CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL14402392 | 0.80 | CETP (0.58) | CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL22057166 | 0.78 | CETP (0.47) | CETPCHRM2CHRM1CHRM3 | |
| SCHEMBL22057298 | 0.77 | CETP (0.46) | CETPCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |