Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933616 | 0.89 | PPARG (0.59) | EPHX1PPARAPPARGEPHX2ACACB | |
| SCHEMBL934426 | 0.84 | EPHX1 (0.49) | EPHX1GRIN2B | |
| SCHEMBL933944 | 0.82 | LDHA (0.54) | EPHX1PPARAPPARGEPHX2 | |
| SCHEMBL934421 | 0.81 | PPARG (0.49) | EPHX1PPARAPPARGEPHX2PPARD | |
| SCHEMBL934005 | 0.80 | EPHX1 (0.60) | EPHX1PPARAPPARGEPHX2ACACB | |
| SCHEMBL23095147 | 0.79 | ACACB (0.46) | EPHX1PPARAPPARGEPHX2ACACB | |
| SCHEMBL16711804 | 0.78 | PPARG (0.75) | PPARAPPARGEPHX2ACACBPTPN1 | |
| SCHEMBL4692054 | 0.77 | ESR1 (0.53) | EPHX1 | |
| SCHEMBL3662060 | 0.76 | CYP1A2 (0.55) | EPHX1HDAC3HDAC1HDAC2 | |
| SCHEMBL2846532 | 0.76 | CYP1A2 (0.55) | EPHX1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |